王会，教授，博士生导师，现任职于徐州医科大学江苏省免疫与代谢重点实验室，现为瑞典卡罗林斯卡学院访问学者(https://ki.se/en/people/hui-wang)。2005年本科毕业于南京大学生物科学系；2008年获得南京大学医学院硕士学位；2012年获得瑞典哥德堡大学医学科学博士学位；2013年瑞典林雪平大学博士后；2014-2018年美国安德森肿瘤中心免疫系博士后。主要研究方向包括（1）淋巴细胞分化与自身免疫性疾病；（2）小胶质细胞功能异常与神经退行性病变。主持瑞典研究理事会国际博士后基金、国家自然科学基金青年和面上项目等。已发表SCI论文58篇，近五年以通讯作者身份在Nat Commun、iScience、Frontier Immunol等杂志发表论文10余篇。论文累计被引用2100余次，H指数27。担任Allergy、Mucosal Immunol等期刊审稿人，参译《詹韦免疫生物学》。已指导硕士研究生21名和博士生研究生3名。

 

 

研究论文（#共同贡献）

2026年

1. Yan W, Zhao Y, Li H, Hong L, Jia Q, Zhu D, Xiang D, Du L, Hu L, Bai R, Xu M, Tang Y, Chen X, Cao Y, Jia W, Wang S, Liu Y, Ren J, Pan S, Shi Y, Gao S, Dong F, Shi J, Li J#, Zheng K#, Yang J#, Zhao S#, Wang H#. Aurka-Bhlhe41 axis prevents premature aging-like microglial dysfunction and promotes remyelination. Nat Commun, 2026.

2. Yan W, Xiang D, Du L, Zhu D, Jia Q, Liu Y, Wang S, Liu L, Guan H, Zhao Y, Jiang G#, Gao S#, Wang H#. Aurkb deficiency disrupts microglial development, homeostasis and hinders remyelination following cuprizone-induced demyelination. iScience, 2026. 29(2):114718.

2025年

3. Smelik M, Diaz-Roncero Gonzalez D, An X, Heer R, Henningsohn L, Li X, Wang H, Zhao Y, Benson M. Combining Spatial Transcriptomics, Pseudotime, and Machine Learning Enables Discovery of Biomarkers for Prostate Cancer. Cancer Res, 2025. 85(13):2514-2526

4. Mahmud A, Mansour Aly DG, Zhao Y, Benson M, Smelik M, Sysoev O, Wang H,Li X. Proteogenomic analysis reveals Arp 2/3 complex as a common molecular mechanism in high risk pancreatic cysts and pancreatic cancer. Sci Rep, 2025. 15(1):3902.

2024年

5. Sch?fer S, Smelik M, Sysoev O, Zhao Y, Eklund D, Lilja S, Gustafsson M, Heyn H, Julia A, Kovács IA, Loscalzo J, Marsal S, Zhang H, Li X, Gawel D #, Wang H#, Benson M#. scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases. Genome Med, 2024. 16(1):42.

6. Ren J, Liu K, Hu L, Yang R, Liu Y, Wang S, Chen X, Zhao S, Jing L, Liu T, Hu B, Zhang X, Wang H#, Li H#. An Efficient Probe-Based Quantitative PCR Assay Targeting Human-Specific DNA in ST6GALNAC3 for the Quantification of Human Cells in Preclinical Animal Models. Mol Biotechnol, 2024.

7. Zou X, Wang K, Deng Y, Guan P, Pu Q, Wang Y, Mou J, Du Y, Lou X, Wang S, Jiang N, Zhou S, Wang H, Du D, Liu X, Hu H, Zhang H. Hypoxia-inducible factor 2alpha promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism. Immunity, 2024. 57(12):2808-2826 e8.

8. Kou Y, Zhang S, Chen J, Shen Y, Zhang Z, Huang H, Ma Y, Xiang Y, Liao L, Zhou J, Cheng W, Zhou Y, Yang H, Liu Z, Wei Y, Wang H, Wang Y. A mouse protozoan boosts antigen-specific mucosal IgA responses in a specific lipid metabolism- and signaling-dependent manner. Nat Commun, 2024. 15(1):7914.

2023年

9. Xu M, Ren J, Jia W, Wang S, Liu Y, Chen X, Shi J#, Wang H#. Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b. Scand J Immunol, 2023:e13309.

10. Liu K, Hu L, Wang S, Chen X, Liu Y, Zhao S, Wang H, Li L,Li H. An efficient qPCR assay for the quantification of human cells in preclinical animal models by targeting human specific DNA in the intron of BRCA1. Mol Biol Rep, 2023. 50(11):9229-9237.

11. Lilja S, Li X, Smelik M, Lee EJ, Loscalzo J, Marthanda PB, Hu L, Magnusson M, Sysoev O, Zhang H, Zhao Y, Sjowall C, Gawel D #, Wang H#, Benson M#. Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases. Cell Rep Med, 2023. 4(3):100956.

12. Gao S, Shi Y, Bai R, Li H, Ren J, Chen X, Hu L, Shi Z, Zhao S, Wang H. Sputum basophils from allergic asthmatic patients do not express IL-7Rα that is essential for TSLP signalling. Scand J Immunol, 2023. 97(1):e13236.

2022年

13. Li X, Lee EJ, Lilja S, Loscalzo J, Schafer S, Smelik M, Strobl MR, Sysoev O, Wang H, Zhang H, Zhao Y, Gawel DR, Bohle B, Benson M. A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets. Genome Med, 2022. 14(1):48.

14. Li H, Tang Y, Ren J, Bai R, Hu L, Jia W, Cao Y, Hong L, Xu M, Gao S, Shi Y, Pan S, Wang L, Zheng K#, Zhao S#, Wang H#. Identification of novel B-1 transitional progenitors by B-1 lymphocyte fate-mapping transgenic mouse model Bhlhe41dTomato-Cre. Front Immunol, 2022. 15:13:946202

15. He C, Gao S, Zhao X, Shi Y, Tang Y, Cao Y, Bai R, Ren J, Zhao S, Shi Z, Wang H. An efficient and cost-effective method for the purification of human basophils. Cytometry A, 2022. 101(2):150-158.

16. Chen X, Hu J, Wang Y, Lee Y, Zhao X, Lu H, Zhu G, Wang H, Jiang Y, Liu F, Chen Y, Kim BS, Zhou Q, Liu X, Wang X, Chang SH,Dong C. The FoxO4/DKK3 axis represses IFN-gamma expression by Th1 cells and limits antimicrobial immunity. J Clin Invest, 2022. 132(18).

17. Bai RX, Chen XZ, Ren JF, Hu L, Li H, Wang H#, He C#. Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN-gamma-induced murine BV2 microglia cells via NF-kappaB signal pathway. Acta Trop, 2022. 235:106650.

综述论文

1. 石言彪, 高偲佳, 王会. 短链脂肪酸调控过敏性疾病研究进展[J]. 四川大学学报（医学版）, 2022, 53(1): 28-34.