杨晶博士毕业于日本高知大学医学部血液内科,作为JSPS外国人特别研究员在日本高知大学医学部免疫学教研室从事白血病免疫治疗研究。曾在美国北卡罗来纳大学教堂山分校放射肿瘤系访学。先后获得江苏特聘教授,江苏双创个人等人才项目资助。主持参与国家自然基金青年项目,江苏省自然科学基金,江苏省高校重大项目等多个项目。承担麻醉衔接班、留学生及硕士/博士研究生《医学免疫学》的部分课程。指导大学生创新项目2项。近五年以第一/通讯作者发表论文9篇,其中SCI 8篇,北大核心1篇。申请专利6件,授权2件。
论文
2022年度
1. Li R, Li X, Zhao J, Meng F, Yao C, Bao E, Sun N, Chen X, Cheng W, Hua H, Li X, Wang B, Wang H, Pan X*, You H*, Yang J*(共通讯), Ikezoe T. Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Theranostics. 2022 Jan 1;12(2):976-998.
2021年度
1. Chen X, Wang C, Sun N, Pan S, Li R, Li X, Zhao J, Tong H, Tang Y, Han J, Qiao J, Qiu H, Wang H*, Yang J*(共通讯), Ikezoe T. Aurka loss in CD19+ B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production. Theranostics. 2021 Mar 4;11(10):4655-4671. IF: 11.556
2. Yang J*(第一/共通讯), Jin A, Han J, Chen X, Zheng J*, Zhang Y*. MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo. Cancer Res. 2021 Feb 15;81(4):898-909. IF :12.7
3. Li R, Sun N, Chen X, Li X, Zhao J, Cheng W, Hua H, Fukatsu M, Mori H, Takahashi H, Ohkawara H, Fukami M, Okamoto M, Hamazaki Y, Zheng K, Yang J*(共通讯), Ikezoe T*. JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages. Front Immunol. 2021 Feb 8;11:589048. IF: 7.5
4. Sun N, Meng F, Zhao J, Li X, Li R, Han J, Chen X, Cheng W, Yang X, Kou Y, Zheng K*, Yang J*(共通讯), Ikezoe T. Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation. Int J Biol Sci. 2021 Mar 25;17(5):1302-1314. IF: 6.56
5. Chen X, Sun N, Li R, Sang X, Li X, Zhao J, Han J, Yang J*(通讯), Ikezoe T. Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis. Int J Biol Sci. 2021 Mar 25;17(5):1263-1276. IF: 6.56
2020年度
1. Han J, Jiang Z, Wang C, Chen X, Li R, Sun N, Liu X, Wang H, Hong L, Zheng K*, Yang J*(共通讯), Ikezoe T. Inhibition of Aurora-A Promotes CD8+ T-Cell Infiltration by Mediating IL10 Production in Cancer Cells. Mol Cancer Res. 2020 Oct;18(10):1589-1602. IF: 4.630
2. Meng F, Sun Q, Zhou D, Li Q, Han J, Liu D, Yang J*(通讯). Inhibition of Aurora-A improves insulin resistance by ameliorating islet inflammation and controlling interleukin-6 in a diabetic mouse model.Adipocyte. 2020 Dec;9(1):609-619. IF:3.146
3. microRNA-125b 经 p53 通路调控 alisertib 耐药细胞代谢的机制研究,中华肿瘤杂志。通讯,2020年接收
2020年度前
Li M, Gao K, Chu L, Zheng J*, Yang J*(共通讯). The role of Aurora-A in cancer stem cells. Int J Biochem Cell Biol. 2018 May;98:89-92. IF:3.673