博士后、副主任医师、副教授、硕士生导师、徐州医科大学青年特聘教授、徐州医科大学杰出青年科技人才“高峰计划”四青人才入选者、江苏省优秀青年基金获得者，江苏省第六期“333高层次人才”，徐州市医学青年后备人才。截至目前以第一作者或通讯作者发表SCI收录论文20余篇。相关研究发表于《Mol Cancer》、《J Exp Clin Cancer Res》、《Angiogenesis》、《Cell Death & Disease》、《Cell proliferation》学术期刊。主持国家自然科学基金2项，江苏省自然科学基金2项，博士后面上项目一等资助1项，徐州重点研发项目1项。并参与国家自然科学基金3项（其中2项为第1参与人）。获江苏省新技术引进奖一等奖一项。任江苏省抗癌协会胃癌专业委员会青年委员，湖南省老年医学学会肠梗阻分会青年委员。

 

1)Tiankang Li, Tingting Zhou, Jin Wu, Heng Lv, Hui Zhou, Mingnan Du, Xiuzhong Zhang, Nai Wu, Shuai Gong, Zeqiang Ren, Pengbo Zhang, Chong Zhang, Guangpu Liu, Xin Liu, Yi Zhang. Plasma exosome-derived circGAPVD1 as a potential diagnostic marker for colorectal cancer. Transl Oncol. 2023 Mar 17;31:101652.

2)Yi Zhang, Lei Xu, Zeqiang Ren, Xin Liu, Jun Song, Pengbo Zhang, Chong Zhang, Shuai Gong, Nai Wu, Xiuzhong Zhang, Chanbin Xie, Zhixing Lu, Min Ma, Yi Zhang, Yifei Chen, Changwei Lin. LINC01615 Maintains Cell Survival in Adaptation to Nutrient Starvation through the Pentose Phosphate Pathway and Modulates Chemosensitivity in Colorectal Cancer. Cellular and Molecular Life Sciences, 2022 Dec 28;80(1):20

3）Zhang Y , Liu X, Wang Y, Lai S, Wang Z, Yang Y, Liu W, Wang H, Tang B. The m6A demethylase ALKBH5-mediated upregulation of DDIT4-AS1 maintains pancreatic cancer stemness and suppresses chemosensitivity by activating the mTOR pathway. Mol Cancer. 2022 Sep 2;21(1):174.

4)Yunze Liu, Lei Xu, Chuanchuan Hao, Jin Wu, Xianhong Jia, Xia Ding, Changwei Lin, Hongmei Zhu, Yi Zhang. Identification and Validation of Novel Immune-Related Alternative Splicing Signatures as a Prognostic Model for Colon Cancer. Front Oncol. 2022 May 26;12:866289.

5)Yi Zhang, Lei Zhou, Yixin Xu, Jingyu Zhou, Tao Jiang, Jiaqi Wang, Chao Li, Xiaoxiong Sun, Hu Song, Jun Song.Targeting SMYD2 inhibits angiogenesis and increases the efficiency of apatinib by suppressing EGFL7 in colorectal cancer. Angiogenesis. 2022 May 3.

6)Hui Zhou, Liyong Zhu, Jun Song, Guohui Wang, Pengzhou Li, Weizheng Li, Ping Luo, Xulong Sun, Jin Wu, Yunze Liu, Shaihong Zhu, Yi Zhang. Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer. Mol Cancer. 2022 Mar 25;21(1):86.

7) Xin Liu, Yunze Liu, Zhao Liu, Changwei Lin, Fanchao Meng, Lei Xu, Xiuzhong Zhang, Chong Zhang, Penbo Zhang, Shuai Gong, Nai Wu, Zeqiang Ren, Jun Song, Yi Zhang. CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner. Mol Cancer. 2021 Sep 8;20(1):114. 

8) Jiaqi Wang, Yi Zhang , Hu Song, Hang Yin, Tao Jiang, Yixin Xu, Lianyu Liu, Hongyu Wang, Hong Gao, Renhao Wang, Jun Song. The circular RNA circSPARC enhances the migration and proliferation of colorectal cancer by regulating the JAK/STAT pathway. Mol Cancer. 2021 Jun 1;20(1):81. 

9) Yunze Liu#, Xin Liu#, Changwei Lin, Xianhong Jia, Hongmei Zhu, Jun Song, Yi Zhang. Noncoding RNAs Regulate Alternative Splicing in Cancer. J Exp Clin Cancer Res. 2021 Jan 6;40(1):11. 

10) Lei Xu, Chong Zhang , Hang Yin, Shuai Gong, Nai Wu, Zeqiang Ren, Yi Zhang. RNA modifications act as regulators of cell death. RNA Biol. 2021 Jul 27;1-11.

11)Bo Tang, Yi Zhang, Wei Wang, Guangying Qi, Fumio Shimamoto. PARP6 suppresses the proliferation and metastasis of hepatocellular carcinoma by degrading XRCC6 to regulate the Wnt/β-catenin pathway. Am J Cancer Res. 2020 Jul 1;10(7):2100-2113. 

12) Fanchao Meng, Xin Liu, Changwei Lin, Lei Xu, Jinjin Liu, Pengbo Zhang, Xiuzhong Zhang, Jun Song, Yichao Yan, Zeqiang Ren, Yi Zhang. SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer. Am J Cancer Res. 2020 Mar 1;10(3):997-1011. 

13) Zhang Y, Wei Y, Li X, Liang X, Wang L, Song J, Zhang X, Zhang C, Niu J, Zhang P, Ren Z, Tang B. microRNA-874 suppresses tumor proliferation and metastasis in hepatocellular carcinoma by targeting the DOR/EGFR/ERK pathway. Cell Death Dis. 2018 Jan 26;9(2):130. 

14) Zhou Hui, Lin Changwei, Zhang Yi, Zhang Xiuzhong, Zhang Chong, Zhang Pengbo, Xie Xingwang, Ren Zeqiang*. miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression. Cell Prolif. 2017 Jun;50(3).