张昕，江苏无锡人，主任医师、医学博士、南京医科大学附属无锡市人民医院麻醉科科主任，美国杜克大学麻醉系Adjunct Assistant Professor。江苏卫生创新团领军人才、江苏特聘医学专家、江苏省“333高层次人才”培养对象。无锡市医学会麻醉学分会候任主任委员、中华医学会麻醉学分会/中国医师协会麻醉科医师分会器官移植麻醉学组委员、江苏省医学会麻醉学分会委员。2016年以来主持及主要参与国家级课题5项。2017年以来发表SCI论文20+篇，被引用400+次。《Frontier in Pain Research》、《Frontier in Molecular Neuroscience》Associate Editor。

• 临床工作

@ 南京医科大学附属无锡人民医院

• 主任医师， 2021

@ 上海交通大学附属第六人民医院麻醉科

• 副主任医师， 2015

• 主治医师， 2009-2015

• 住院医师，2002-2009

• 研究工作

    Adjunct Assistant Professor，麻醉系，美国杜克大学 2021

    Assistant Professor，麻醉系，美国杜克大学 2020

    Research Scientist,  麻醉系，美国杜克大学 2019

    博士后,  麻醉系，美国杜克大学 2016

    博士，上海交交通大学医学院，2015

    硕士，上海交交通大学医学院，2011

    本科（临床医学），上海第二医科大学(现上海交通大学医学院)，2002

 

·        Wu X, Miao S, Zhou Y, Wu T, Chen J, Wang G, Zhang X^#.The comparative impact of central vs. peripheral VA-ECMO cannulation on postoperative graft dysfunction in lung transplantation: a retrospective analysis. Front Cardiovasc Med. 2025 Feb 25;12:1512742.

·        Yang J, Wu X, Miao S, Chen J, Tian T, Chen W, Wang G, Zhang X^#, Zhou Y. A nationwide survey on current practices in anesthesia management for lung transplantation in China. Sci Rep. 2025 Jul 7;15(1):24314. 

·        Tong F, Liu S, Zhang C, Gu X, Yang H, Zhou B, Wang YY, Chen J, Qu Q, Gong Y, Pan H, Liang C, Li C, Zhang X^#, Han Q. Elevated vesicular Zn2+ in dorsal root ganglion neurons expressing the transporter TMEM163 causes age-associated itchy skin in mice. PLoS Biol. 2024 Nov 27;22(11):e3002888. 

·        Wang Y, Kim SH, Klein ME, Chen J, Gu E, Smith S, Bortsov A, Slade GD, Zhang X^#, Nackley AG. A mouse model of chronic primary pain that integrates clinically relevant genetic vulnerability, stress, and minor injury. Sci Transl Med. 2024 Apr 10;16(742):eadj0395.

·        Lu S, Zhang Y, Wang Z, Zhang L, Zhang X^#. Editorial: Molecular mechanism of neuroimmune modulation and synaptic plasticity in acute and chronic pain, volume II. Front Mol Neurosci. 2024 Sep 12;17:1484826. 

·        Zhang Q, Zhu L, Yuan S, Lu S, Zhang X^#. Identifying risk factors for hypoxemia during emergence from anesthesia in patients undergoing robot-assisted laparoscopic radical prostatectomy. J Robot Surg. 2024 May 7;18(1):200. doi: 10.1007/s11701-024-01964-0. PMID: 38713381.

·        Zhang L, Zhang X*, Wang Z, Li Y. Editorial: Molecular mechanism of neuroimmune modulation and synaptic plasticity in acute and chronic pain. Front Mol Neurosci. 2023 Jun 9;16:1224792. 

·        Scarneo S, Zhang X*,, Wang Y, Camacho-Domenech J, Ricano J, Hughes P, Haystead T, Nackley AG. Transforming Growth Factor-β-Activated Kinase 1 (TAK1) Mediates Chronic Pain and Cytokine Production in Mouse Models of Inflammatory, Neuropathic, and Primary Pain. J Pain. 2023 Sep;24(9):1633-1644. 

·        Zhou Y, Qin Z, Wang G, Chen W, Zhang X^#. Current status and training needs of trainee anesthesiologists in lung transplantation anesthesia in China: A single-center survey. Heliyon. 2022 Dec 19;8(12):e12428. 

·        Qian Y, Huang Z, Wang G, Han J, Zhou D, Ding H and Zhang X^# (2022), Low-dose naloxone for prophylaxis of sufentanil-induced choking and postoperative nausea and vomiting. Front. Pharmacol. 13:1050847. 

·        Wang Y-W, Wang L, Yuan S-J, Zhang Y, Zhang X^#  and Zhou L-T (2022) Postoperative Cognitive Dysfunction and Alzheimer’s Disease: A Transcriptome-Based Comparison of Animal Models. Front. Aging Neurosci. 14:900350. 

·        Wang Y, Scarneo SA, Kim SH, Zhang X, Chen J, Yang KW, Hughes P, Haystead T, Nackley AG. Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain. Pain. 2022 Jun 1;163(6):1091-1101. 

·        Chen Y, Wang ZL, Yeo M, Zhang QJ, López-Romero AE, Ding HP, Zhang X, Zeng Q, Morales-Lázaro SL, Moore C, Jin YA, Yang HH, Morstein J, Bortsov A, Krawczyk M, Lammert F, Abdelmalek M, Diehl AM, Milkiewicz P, Kremer AE, Zhang JY, Nackley A, Reeves TE, Ko MC, Ji RR, Rosenbaum T, Liedtke W. Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine. Gastroenterology. 2021 Jul;161(1):301-317.e16. 

·        Zhang X*,, Kanter, K., Chen, J., Kim, S., Wang, Y., Adeyemi, C., O'Buckley, S. C., and Nackley, A. G. (2020) Low catechol-O-methyltransferase and stress potentiate functional pain and depressive behavior, especially in female mice. Pain 161, 446-458

 

 

 

• β2肾上腺素能受体调控皮肤角化细胞活化在慢性重叠型疼痛状态中的机制研究，2023.1-2026.12，国自然，52万，主持

• 江苏卫生创新团队，2024.1-2026.12，200万

• 江苏特聘医学专家，2023.1-2025.12，100万

• A novel clinically- relevant mouse model of chronic overlapping pain conditions for screening analgesics，2022.4-2023.3，National Institutes of Health（美国国立卫生研究院），35万（美金），主持（PI）

• 皮肤角化细胞β肾上腺素能受体参与调控神经病理性疼痛的机制研究，2022/1-2023/12，无锡市卫生健康委科研重大项目，主持

• 糖尿病性神经痛中经BDNF/TrkB通路调控小胶质细胞极化平衡的机制研究，2015.1-2017.12，国自然，23万，主持

 

l  2023年度  江苏卫生创新团队领军人才

l  2022年度  江苏特聘医学专家

l  2021年度 江苏省“333”人才第3层次培养对象