2021.7-现在,徐州医科大学,基础医学院,教授;
2017.3-2021.3,哈佛大学医学院麻省总医院,博士后;
2015.7-2017.2,中国科学院昆明动物研究所,徐林课题组,助理研究员;
2008.9-2015.6,中国科学技术大学,神经生物学, 博士;
2004.9-2008.7,安徽师范大学,生物科学专业,本科。
研究方向
以动物模型为基础,运用在体钙成像(Miniscope)、电生理(在体场电位和离体膜片钳)、化学遗传学操控、行为药理等研究记忆形成和提取的机制,寻求阿尔兹海默病应对策略。
论文发表
1. Zhou H*, Li HY*, et al.,Gomperts SN. Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer’s disease. Scientific Reports. 2022; 12:21022.
2. Yu CL,et al., Richter-Levin G, Xu L*, Zhou H*. Developing of focal ischemia in the hippocampus or amygdala reveals a regional compensatory rule for fear memory acquisition. eNeuro. 2021 (10.1523).
3. Zhou H, et al., Hyman BT, Gomperts SN. Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle. eLife. 2019 03 07; 8. Featured paper.
4. Zhou H*, Xiong GJ*, Jing L*, Song NN*, Pu DL, et al., Xu L. The interhemispheric CA1 circuit governs rapid generalisation but not fear memory. Nature Communications. 2017 12 19; 8(1):2190.
5. Yu D*, Zhou H*, Zou L*, et al., Xu L, Mao R. Hippocampal Administration of Levothyroxine Impairs Contextual Fear Memory Consolidation in Rats. Front Cell Neurosci. 2017; 11:223.
6. Jiao CX*, Zhou H*, Yang CX, et al., Zhou QX. Protective efficacy of a single salvianolic acid A treatment on photothrombosis-induced sustained spatial memory impairments. Neuropsychiatric Dis Treat. 2017; 13:1181-1192.
7. Zhou H, Zhou Q, Xu L. Unilateral hippocampal inactivation or lesion selectively impairs remote contextual fear memory. Psychopharmacology. 2016 Oct; 233(19-20):3639-46.
8. Zhou H, Yu CL, et al., Zhou QX, Xu L. NMDA and D1 receptors are involved in one-trial tolerance to the anxiolytic-like effects of diazepam in the elevated plus maze test in rats. Pharmacol Biochem Behav. 2015 Aug; 135:40-5.
9. Yu D*, Zhou H*, Yang Y, et al., Xu L, Mao R. The bidirectional effects of hypothyroidism and hyperthyroidism on anxiety- and depression-like behaviors in rats. Hormones Behavior. 2015 Mar; 69:106-15.
10. Yu CL*, Zhou H*, et al., Mao RR, Xu L. Whole-scale neurobehavioral assessments of photothrombotic ischemia in freely moving mice. Journal of Neuroscience Methods. 2015 Jan 15; 239:100-7.